Bis-esters of alkanediols as antibacterial agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

CPC

260/113

IPC codes

C07D 499/44 (2006.01) C07D 499/00 (2006.01)

Type

Patent

Patent number

CA 1176242

Description

BIS-ESTERS OF ALKANEDIOLS AS ANTIBACTERIAL AGENTS Abstract 6-Acylaminopenicillanoyloxymethyl esters and 1- (6-acylaminopenicillanoyloxy)ethyl esters of 2-beta- acetoxymethyl-2-alpha-methyl-(5R)penam-3-alpha- carboxylic acid l,l-dioxide are useful as antibacterial agents. The 6-aminopenicillanoyloxymethyl ester, the 1-(6-aminopenicillanoyloxy)ethyl ester and certain other mono-substituted methyl and ethyl esters of 2- beta-acetoxymethyl-2-alpha methyl-(5R)penam-3-alpha- carboxylic acid l,l-dioxide are useful intermediates to the aforesaid antibacterial agents.

Application Number

396680

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