Aldose reductase inhibiting 5-(2-...

Details Aldose reductase inhibiting 5-(2-... Aldose reductase inhibiting 5-(2-...

C - Chemistry, Metallurgy

07

D

260/310.1

C07D 277/34 (2006.01) C07C 43/225 (2006.01) C07C 45/51 (2006.01) C07C 59/64 (2006.01)

Patent

CA 1233470

ALDOSE REDUCTASE INHIBITING 5-(2- ALKOXYPHENYL)THIAZOLIDINEDIONES Abstract A series of 5-(2-alkoxyphenyl)thiazolidinediones and pharmaceutically acceptable salts thereof useful as hypoglycemic agents, aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications; intermediates therefore; and processes for preparation of said compounds. (IV) Image wherein R is alkyl having from one to four carbon atoms; X is fluoro, chloro or bromo; and Y is hydrogen, chloro, lower alkyl or lower alkoxy.

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