Phenolic thioethers, sulfoxides, and disulfides as...

C - Chemistry – Metallurgy – 07 – C

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C07C 317/46 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/34 (2006.01) A61K 31/365 (2006.01) C07C 323/62 (2006.01)

Patent

CA 1327050

ABSTRACT The compounds of the present invention comprise substituted phenolic thioethers, sulfoxides, and disulfides that are specific inhibitors of 5-lipoxygenase and which, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.

568445

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