Pharmaceutical agent for the treatment of diabetes mellitus

Details Pharmaceutical agent for the treatment of diabetes mellitus Pharmaceutical agent for the treatment of diabetes mellitus

C - Chemistry, Metallurgy

07

K

167/103.41

C07K 14/625 (2006.01) C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1236012

HOE 83/F 142 Abstract of the Disclosure: The invention relates to medicaments consisting of a physiologically acceptable excipient and an active compound combination of a) an insulin derivative of the formula I Image (I) in which R1 denotes H or H-Phe, R30 represents the radi- cal of a neutral L-aminoacid and R31 represents a physio- logically acceptable organic group of basic character with up to 50 carbon atoms, with an isoelectric point between 5.8 and 8.5, and b) an insulin of the formula I in which R1 denotes H or H-Phe, R30 represents Ala, Thr or Ser and R31 de- notes OH, and to its use for the treatment of diabetes mellitus.

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