Preparation process of n-acylphenylalanines

Details Preparation process of n-acylphenylalanines Preparation process of n-acylphenylalanines

C - Chemistry, Metallurgy

07

D

260/516, 260/352

C07D 317/60 (2006.01) C07C 103/46 (1985.01) C07C 103/84 (1985.01)

Patent

CA 1235420

- 39 - ABSTRACT A process for preparing an N-acylphenyl- alanine represented by the formula (I): Image (I) wherein R3 and R4 are independently a hydrogen atom or an alkyl, alkoxy, phenoxy, hydroxy or methylene- dioxy group, and R is a methyl or phenyl group, which comprises catalytically reducing an N-acyl-.beta.-phenyl- serine represented by the formula (II): Image (II) wherein R1 and R2 are independently a hydrogen atom or an alkyl, alkoxy, phenoxy, benzyloxy or methylene- dioxy group, and R has the same meaning as defined in the formula (I), in the presence of a reducing catalyst and an acid, in a solvent.

481506

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