C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/355.1
C07D 313/00 (2006.01) C07H 17/08 (2006.01) C12P 17/08 (2006.01) C12P 19/62 (2006.01)
Patent
CA 1181746
Abstract of the Invention Mycarosyltylactone (5-O-mycarosyl-20- dihydro 20,23-dideoxytylonolide) which has the formula: Image 3,4'-diacyl ester derivatives of mycarosyltylactone wherein each of said esters is an ester of a mono- carboxylic acid or a hemi-ester of dicarboxylic acid, each of 1 to 18 carbon atoms, and the corresponding 3-acyl ester derivatives of tylactone, are useful intermediates in the preparation of macrolide anti- biotics. New methods for making tylactone and the 3-acyl ester derivatives of tylactone are provided.
382652
Hamill Robert L.
Wild Gene M.
Eli Lilly And Company
Kirby Eades Gale Baker
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