Mycarosyltylactone

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

260/355.1

C07D 313/00 (2006.01) C07H 17/08 (2006.01) C12P 17/08 (2006.01) C12P 19/62 (2006.01)

Patent

CA 1181746

Abstract of the Invention Mycarosyltylactone (5-O-mycarosyl-20- dihydro 20,23-dideoxytylonolide) which has the formula: Image 3,4'-diacyl ester derivatives of mycarosyltylactone wherein each of said esters is an ester of a mono- carboxylic acid or a hemi-ester of dicarboxylic acid, each of 1 to 18 carbon atoms, and the corresponding 3-acyl ester derivatives of tylactone, are useful intermediates in the preparation of macrolide anti- biotics. New methods for making tylactone and the 3-acyl ester derivatives of tylactone are provided.

382652

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