Occlusive body for administering a physiologically active...

A - Human Necessities – 61 – K

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A61K 9/70 (2006.01) A61M 35/00 (2006.01) A61M 37/00 (2006.01)

Patent

CA 1335256

An occlusive body such as a patch, pad or bandage is provided which incorporates a reservoir containing a physiologically active substance, the reservoir incorporating a membrane permeable to the active substance and either the membrane being hydrophilic and the reservoir contents being hydrophobic or vice versa. The reservoir also contains a filler material such as methyl cellulose which immobilises the reservoir contents e.g. by forming a gel. The dosage rate of the active substance through the membrane when the latter is applied to the skin of a subject is substantially constant until much of the dose has been delivered from the reservoir.

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