5-(1-cyano-n-methyl-n-phenethyl)-alkylamino-2,2-8-trimethyl...

Details 5-(1-cyano-n-methyl-n-phenethyl)-alkylamino-2,2-8-trimethyl... 5-(1-cyano-n-methyl-n-phenethyl)-alkylamino-2,2-8-trimethyl...

C - Chemistry, Metallurgy

07

D

167/231, 260/276

C07D 491/056 (2006.01) A61K 31/44 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1286300

A B S T R A C T The invention relates to new 5-(1-cyano-1-alkyl-N- methyl-N-methoxy-phenethyl)-alkylamino-2,2,8 - trimethyl- 4H - dioxino-(4,5-c)-pyridine derivatives of the formula Image and therapeutically acceptable salts of these compounds, to a preparation process of the same comprising reacting, in stoichiometric proportions, the corresponding 5-(1-cyano-1-R1)- methyl-2,2,8-trimethyl-4H-dioxino-(4,5-c)-pyridine on the appropriate [N-methyl-N-(methoxy-phenethyl)] - .omega. -alkyl chloride and, finally, to therapeutic compositions containing said derivatives as active ingredients.

493578

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