Octahydro indenofuran derivatives, their preparation and...

Details Octahydro indenofuran derivatives, their preparation and... Octahydro indenofuran derivatives, their preparation and...

C - Chemistry, Metallurgy

07

D

167/245, 260/366

C07D 307/92 (2006.01) A61K 31/365 (2006.01) C07D 307/93 (2006.01)

Patent

CA 1307279

ABSTRACT OF THE DISCLOSURE This invention relates to indenofuran derivatives of the formula: Image wherein R stands for a Image group optionally substituted on the phenyl ring by Alk, OH or OAlk, Alk being a lower straight or branched alkyl group up to C5, to the preparation of these compounds and to therapeutic compositions containing the same. The compounds according to the present invention are useful as a precursor for the synthesis of both Ginkgolides and of related derivatives presenting PAF-Acether antagonist activity. Most of these compounds also present interesting therapeutic activity in the field of anaphylaxy.

582168

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