Method of diagnosis and an outfit for carrying it out

Details Method of diagnosis and an outfit for carrying it out Method of diagnosis and an outfit for carrying it out

G - Physics

01

N

150/11

G01N 37/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 1170555

Case 4-12268/+ A method of diagnosis and an outfit for carrying it out Abstract A novel method of diagnosis of atherosclerosis comprises comparing the migration of endothelial cells or of cells of endothelium-like morphology in vitro, in the presence of serum from the person being examined, with the migration of identical cells in the presence of serum from healthy persons or of other standard sera, and interpreting a retuced migration in the presence of serum of the person being examined as being an indication of the possible existance of atherosclerosis in this person. The cell migration is measured for example on monolayer cell cultures of pig aorta endothelial cells or of Balb/c 3T3-A31 cells, in which cultures a portion of the cellular layer has been removed. An outfit for carrying out the method contains the materials and devices necessary for the purpose.

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