Preparation process of novel derivatives of piperidin 3-yl...

Details Preparation process of novel derivatives of piperidin 3-yl... Preparation process of novel derivatives of piperidin 3-yl...

C - Chemistry, Metallurgy

07

D

260/279

C07D 401/04 (2006.01)

Patent

CA 1195332

PRECIS DE LA DIVULGATION: L'invention concerne un procédé pour préparer les produits (I): Image (I) où R est hydrogène, alkyle (1-8C) ou aralkyle (7-12C), X est hydrogène, halogène, alkyle (1-8C) ou, avec c, oxo, Y est alkyle (1-8C), c forme avec d une liaison C-C ou, avec X, est oxo, d est hydrogène ou forme avec c une liaison C-C, Z est hydrogène, CH3, alkyle ou hydroxyalkyle (2-8C), aryloxyalkyle (7-12C), aralkyle (7-12C) éventuellement substitué par halogène, alkoxy (1-4C), alkyle (1-4C), OH, CF3, OCF3, NO2 ou NH2, ou Z est cycloalkylalkyle (4-12C), alkényle ou alkynyle (3-8C), leurs sels d'addition avec les acides. Les produits I et leurs sels sont utiles comme médicaments, notamment stimulants dopaminergiques et anti- anoxiques.

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