C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/7.06
C07K 14/66 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1105925
ABSTRACT OF THE DISCLOSURE There are disclosed polypeptide compositions having the following amino acid sequence as the active site: ARG-LYS-ASP-VAL-TYR This polypeptide has the capability of inducing the differentiation of T-lymphocytes but not of complement receptor (CR+) B-lymphocytes and thus is useful in a number of therapeutic areas. Also provided are derivatives of the pentapeptide, novel intermediate polypeptides, methods of manufacture of the peptides, therapeutic compositions, and methods for use of the compositions. - 1 -
296490
Goldstein Gideon
Schlesinger David H.
Johnson & Hicks
Sloan-Kettering Institute For Cancer Research
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