Drug particles having constant release and immediate release

Details Drug particles having constant release and immediate release Drug particles having constant release and immediate release

A - Human Necessities

61

K

167/240, 167/262

A61K 9/56 (2006.01) A61K 9/50 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1275048

ABSTRACT DRUG PARTICLES HAVING CONSTANT RELEASE AND IMMEDIATE RELEASE Drug particles are disclosed which reduce the variation in dissolution rate with time frequently found with sustained-release dosage forms. Additionally the particles give very rapid absorption of the drug by the body. This is achieved by coating the drug particle with a first coating of an enteric material, a second coating of a material which is insoluble at any pH and acts as a diffusion barrier for the drug active and a final, third, coating of a mixture of the drug and hydrophilic excipients.

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