Replication of virulent treponema pallidum in tissue culture

C - Chemistry – Metallurgy – 12 – N

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167/135, 195/33,

C12N 1/20 (2006.01) A61K 39/02 (2006.01) C12N 7/00 (2006.01)

Patent

CA 1174992

ABSTRACT OF THE INVENTION A method and materials are provided for replication of virulent Treponema pallidum in tissue culture, employing a modified Eagle's minimum essential medium, wherein said in vitro cultivated T. palladium can be utilized as a source of relatively pure organisms, free of host tissue, for the preparation of a vaccine against syphilis and as a source of organisms for use in specific immunological tests for syphilis.

396867

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