C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/207, 260/328
C07D 311/58 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) C07D 311/60 (2006.01) C07D 311/64 (2006.01) C07D 311/68 (2006.01) C07D 335/06 (2006.01) C07D 413/04 (2006.01)
Patent
CA 1247615
Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture. Abstract of the Disclosure The invention relates to pharmaceutical preparations containing compounds of formula I Image (I), in which X1 and X2, independently of each other, represent hydrogen, halogen, unsubstituted or substituted amino or a quaternary ammonium salt; etherified or esterified hydroxy; free, etherified, esterified or oxidized mercapto; nitro; functionally modified formyl; free or functionally modified carboxyl; acyl; an unsubstituted or substi- tuted hydrocarbon radical, or an unsubstituted or substituted heterocyclic radical; with the proviso that at least one of the radicals X1 and X2 is bonded by a carbon atom to the ring system and with the proviso that X1 and X2 cannot be together halogen and formyl; in which Y represents oxygen, sulfur, sulfinyl or sulfonyl but must be sulfur, sulfinyl or sulfonyl, if X1 is hydrogen and X2 is formyl; and the rings A and B are each unsubstituted or substi- tuted; or pharmaceutically acceptable salts of such compounds that con- tain a salt-forming group, and to novel compounds of formula I. The compounds are useful e.g. for the treatment of diseases of the respiratory tract and of liver diseases. The are prepared by methods known per se.
462008
Narbel Philippe M.
Rimbault Christian G.
Fetherstonhaugh & Co.
Zyma S.a.
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