Heterocyclic compounds and their preparation and use

Details Heterocyclic compounds and their preparation and use Heterocyclic compounds and their preparation and use

C - Chemistry, Metallurgy

07

D

167/211, 260/271

C07D 471/14 (2006.01) A61K 31/495 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07F 7/08 (2006.01)

Patent

CA 1308712

ABSTRACT New heterocyclic compounds having the general formula Image wherein R is Image , Image , CO2R' or CONR'R'', wherein R' and R'' independently are C1-6-alkyl, C3-7-cycloalkyl or C1-6-alkoxymethyl; -A- is -C(=O)-NR'''-, -NR'''-C(=O)-, or Image , wherein R''' is C1-6-alkyl; X is C or N; and R4 is hydrogen, halogen, CN, C1-6-alkyl, C1-6-alkynyl, tri- methylsilyl-C1-6-alkynyl, aryloxy which may be substituted with halogen, aralkoxy, C3-7-cycloalkoxy which may be sub- stituted with one or more C1-6-alkyl groups,or NR''''R''''', wherein R'''' and R''''' independently are C1-6-alkyl or together with the nitrogen atom form a 3-7 membered hetero- cyclic ring. The compounds are useful in psychopharmaceutical preparati- ons as anticonvulsants, anxiolytics, hypnotics, and nootro- pics.

561758

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