Preparation of n-(methoxyphenacyl)-amine derivatives

Details Preparation of n-(methoxyphenacyl)-amine derivatives Preparation of n-(methoxyphenacyl)-amine derivatives

A - Human Necessities

61

K

260/579.2

A61K 31/135 (2006.01)

Patent

CA 1220224

ABSTRACT OF THE DISCLOSURE The invention relates to new N-(methoxy- phenyl)-amine derivatives selected from the group consisting of (i) the N-(methoxyphenacyl)-alkylamines of the general formula (I) Image wherein A is OCH3, and R is C3-C8-alkyl or C3-C8-hydroxyalkyl; and, (ii) addition salts thereof. These new derivatives are useful as pharmaceuticals, in particular as peripheral vasodilating agents. Their method of pre- paration is based upon the following reaction scheme: Image

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