Granular tricalcium phosphate compositions suitable for...

Details Granular tricalcium phosphate compositions suitable for... Granular tricalcium phosphate compositions suitable for...

A - Human Necessities

61

K

18/1120, 23/64

A61K 9/16 (2006.01) A61K 9/20 (2006.01) B01J 2/22 (2006.01) C01B 25/32 (2006.01)

Patent

CA 1325707

GRANULAR TRICALCIUM PHOSPHATE COMPOSITIONS SUITABLE FOR DIRECT COMPRESSION TABLETING ABSTRACT OF THE DISCLOSURE A granular directly compressible tricalcium phosphate having a particle size sufficient for efficient direct compression tableting, can be prepared by densifying compacting tricalcium phosphate to a particle size sufficient for wet granulation. The wet granulatable tricalcium phosphate can be easily wet granulated with a binder. The product wets easily, does not absorb excessive binder, and dries easily in a short period of time. The wet granulated tricalciumn phosphate exhibits good compressibility in direct compression tableting.

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