Prostaglandins and prostacyclins, processes for their...

Details Prostaglandins and prostacyclins, processes for their... Prostaglandins and prostacyclins, processes for their...

C - Chemistry, Metallurgy

07

D

260/235.01

C07D 233/61 (2006.01) C07C 405/00 (2006.01) C07D 263/10 (2006.01) C07D 263/14 (2006.01) C07D 277/10 (2006.01) C07D 417/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1215974

ABSTRACT OF THE DISCLOSURE The invention provides compounds of the general formula Image I, in which R1 represents prostaglandin or prostacyclin radicals, Y represents oxygen, sulphur or imino, Q represents the radi- cal (CR6R7)p, in which p is 0 or 1, R2 represents hydrogen, (C1-C6)-alkyl, C1-C4-alkoxycarbonyl, cyano or di-(C1-C4)- alkylaminocarbonyl, or R2 together with R5 represents a direct bond, R3, R4, R5, R6 and R7 each represent hydrogen or methyl, or R3 and R4 together represent trimethylene, tetra- methylene or 1,3-butadienylene when R2 and R5 together re- pesent a direct bond, their manufacture and their use, for example as hypertensive or abortive agents.

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