Thiazine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/243.21

C07D 513/04 (2006.01) C07D 333/38 (2006.01)

Patent

CA 1217187

Abstract The novel 4-hydroxy-2-methyl-3-(2-pyridylcarbamoyl)-6- -trifluoromethyl-2H-thieno[2,3-e]-1,2-thiazine 1,1-dioxide of the formula Image I and its pharmaceutically acceptable salts possess valuable pharmacodynamic properties. In particular, they display antiinflammatory, analgesic and antirheumatic activities and they are readily accessible by reacting a corresponding alkyl ester with 2-aminopyridine and, if desired, sub- sequent salt formation.

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