Method for the preparation of fibrates

Details Method for the preparation of fibrates Method for the preparation of fibrates

C - Chemistry, Metallurgy

07

C

260/514.4, 260/4

C07C 59/70 (2006.01) C07C 67/31 (2006.01) C07C 69/712 (2006.01) C07C 69/73 (2006.01) C07C 233/81 (2006.01)

Patent

CA 1282424

ABSTRACT OF THE DISCLOSURE The present invention relates to a method for the preparation of fibrates of the formula I according to the mechanism: Image (V) + Image (VI) Image (I) in which R1 represents especially a halogen atom (in particular F, Cl or Br, the preferred halogen atom being Cl) or an acetyl, (4-chlorophenyl)hydroxymethyl, 4-chlorobenzoyl or 2-(4-chlorobenzamido)ethyl group and R2 represents a C1-C4 alkyl group in which the hydrocarbon chain is linear or branched, the reaction V + VI being carried out without a solvent.

535685

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