Urea derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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260/546, 260/545

C07C 335/12 (2006.01) C07C 275/24 (2006.01)

Patent

CA 1191862

ABSTRACT A compound, or pharmaceutically acceptable salt thereof, having the formula: Image wherein X is O or S; wherein n = 1 or O; wherein R is C3-C12 alkyl or aralkyl, branched or unbranched, aryl or haloaryl, or C3-C22 alkenyl, branched or unbranched; wherein Rl is OCH3, and wherein R2 is OH. These urea derivatives have analgesic and anti-irritant activity when administered to humans and lower animals.

404688

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