Process for the preparation of 2-acyl-1,3,4,6,7,11b-...

C - Chemistry – Metallurgy – 07 – D

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260/265.5

C07D 471/04 (2006.01) C07D 241/06 (2006.01) C07D 241/08 (2006.01)

Patent

CA 1202629

- 1 - ABSTRACT 2-Acyl-1,3,4,6,7,11b-hexahydro-2H-pyrazino-[2,1-a]-4- isoquinoleinones of the formula Image are prepared from 4-acyl-2,6-dioxopiperazines by reaction with a phenethyl halide, selective reduction of one of the oxo groups and cyclisation, by the novel intermediates of formula Image in which Y represents O or H,OH.

420124

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