Controlled - release device

A - Human Necessities – 61 – K

Patent

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167/164

A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1329125

ABSTRACT OF THE DISCLOSURE: The invention relates to a controlled-release device having a core comprising one or more water-soluble ingredients, at least one of said water-soluble ingredients being the ingredient which it is desired to release in a controlled manner, said core being surrounded by a semi- permeable membrane coat in which are dispersed water-soluble particle(s) of such a number as to give rise by dissolution, upon placing the device in an aqueous environment, to one or two pores extending through the coat enabling communication between the core and the exterior of the device. This device provides a continuous discharge of an ingredient thereof in a controlled manner, and to multiparticulate compositions containing such devices. The invention also relates to a method for preparing such a device and to multiparticulate controlled released composition comprising a plurality of devices.

572526

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