Glycopeptide recovery process

Details Glycopeptide recovery process Glycopeptide recovery process

C - Chemistry, Metallurgy

07

K

195/78, 530/9

C07K 9/00 (2006.01)

Patent

CA 1338002

A process for recovering vancomycin-type glycopeptide antibiotics which comprises 1) commingling the fermentation medium in which the antibiotic is produced with a polystyrene divinylbenzene resin such as Dow XFS-43278-00*, 2) separating the resin from the medium and 3) eluting the antibiotic from the resin. This improvement avoids preliminary filtration and pH adjustment of the broth, simplifies waste-disposal problems and eliminates antibiotic losses due to mycelial adsorption and filtration.

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