Flavanone derivatives

Details Flavanone derivatives Flavanone derivatives

C - Chemistry, Metallurgy

07

D

260/230, 167/244

C07D 311/32 (2006.01) A61K 31/35 (2006.01) C07D 311/30 (2006.01) C07D 407/00 (2006.01) C07F 9/655 (2006.01) C07H 15/203 (2006.01) C07H 15/226 (2006.01)

Patent

CA 1270484

Flavanone derivatives A b s t r a c t New flavanone derivatives of the formula I Image I wherein Ar1 and Ar2 are each phenyl which is unsubsti- tuted or monosubstituted to trisubstituted by OH, alkyl, alkoxy, acylamino, halogen, COOalkyl and/or NO2 and/or substituted by a methylenedioxy group, and the alkyl, alkoxy and acyl groups each have 1-7 C atoms, but wherein the HO group is only in the 6-position if at least one of the radicals Ar1 and Ar2 is substituted phenyl, and the phosphoric acid esters thereof and the salts of these compounds display antiallergic effects. Salts of the I- phosphoric acid esters with aminoglycoside antibiotics are outstandingly stable and possess advantageous kinetics of liberation.

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