Method for the diagnosis of whooping-cough and a test kit...

C - Chemistry – Metallurgy – 12 – Q

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150/14, 167/37

C12Q 1/00 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01)

Patent

CA 1286604

ABSTRACT A method for the diagnosis of whooping-cough is described. The method is carried out such that a sample of body fluid from a patient is incubated with at least a part of a pertussis toxin- sensitive, chromatophore containing fish-scale during a predeter- mined suitable period of time, that the fish-scale colour then is subjected to a first visual inspection, optionally by means of a microscope, that a substance inducing a colour change in the fish- scales is added, that the fish-scale colour then is subjected to a second visual inspection, optionally by means of the microscope and that the fish-scale colour first observed is compared with the subsequently observed fish-scale colour, the absence of a colour change, or a slight colour change, indicating the presence of pertussis toxin in the body fluid sample. A test kit for carrying the method into effect is described as well.

554315

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