Esters of mercapto acyl-carnitines, process for their...

C - Chemistry – Metallurgy – 07 – C

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C07C 323/52 (2006.01) A61K 31/095 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/22 (2006.01) A61K 31/23 (2006.01) A61K 31/24 (2006.01) A61K 31/255 (2006.01) C07C 319/00 (2006.01)

Patent

CA 1167864

"Esters of mercapto acyl-carnitines, process for their prepara- tion and pharmaceutical compositions containing same". Abstract of the disclosures A novel class of esters of mercapto acyl-carnitines is dis- closed, wherein the mercapto acyl radical is the radical of sat- urated mercapto acids having from 2 to 10 carbon atoms. These esters of mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding ester of halogen acyl-carnitine and then substituting therein, by nucleophylic substitution, the -SH group for the halogen atom. These esters of mercapto acyl-carnitines are useful therapeu- tic agents, e.g. for the treatment of intoxications and burns, and as mucolytic agents.

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