Synthesis of deazapurine nucleosides

C - Chemistry – Metallurgy – 12 – P

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C12P 19/38 (2006.01) C07H 19/052 (2006.01) C12P 19/28 (2006.01)

Patent

CA 1162155

B325 ABSTRACT A method for the preparation of 4-substituted-1-.beta.-D-ribofuranosyl- lH-imidazo-[4,5-c]-pyridines by enzymatic ribosylation of the corresponding 4-substituted-lH-imidazo-[4,5-c]-pyridine is disclosed. In particular the prepar- ation of 4-amino-1-.beta.-D-ribofuranosyl-lH-imidazo-[4,5-c]-pyridine(3-deazadeno- sine) is described.

375911

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