Process for preparing human plasma fractions containing...

Details Process for preparing human plasma fractions containing... Process for preparing human plasma fractions containing...

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) C07K 16/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1168152

TITLE: AN IMPROVED PROCESS FOR PREPARING HUMAN PLASMA FRAC- TIONS CONTAINING IMMUNE GLOBULIN (IgG) ABSTRACT An improved process for preparing human plasma frac- tions containing immune globulin (IgG) which is suitable for intravenous use comprises the use of a dilute solution con- taining IgG as starting material, preferably obtained as an eluate from the chromatographic separation of plasma on a DEAE-Sephadex or a QAE-Sephadex column. The dilute solution containing IgG is treated with a mixture of sodium chloride and glycine and the dilute solution thus obtained is subjected to ultrafiltration to provide a concentrated solution contain- ing IgG. The latter solution may, if desired, be freeze-dried to provide a solid composition of matter containing IgG.

388332

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