Sustained-release, oral pharmaceutical forms of administration

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/137 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/18 (2006.01) A61K 31/192 (2006.01) A61K 31/196 (2006.01) A61K 31/428 (2006.01) A61K 31/54 (2006.01) A61K 31/616 (2006.01) A61P 13/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2382098

The invention relates to oral pharmaceutical forms of administration with an at least partially delayed action. The pharmaceutical active agent contained in said forms of administration, tramadol, is at least partially in the form of a compound formed in situ with a water solubility <= 100 mg/ml. The invention also relates to methods for preparing the inventive forms of administration.

L'invention concerne des formes de présentation pharmaceutiques orales au moins partiellement à action retardée dont le principe actif pharmaceutique tramadol est présent au moins partiellement sous forme de composé formé in situ et ayant une solubilité dans l'eau </= 100 mg/ml. L'invention concerne également leur procédé de production.

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