An improved process for the production of desloratadine

Details An improved process for the production of desloratadine An improved process for the production of desloratadine

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01)

Patent

CA 2499125

An improved process for the production of Desloratadine is described wherein Loratadine is reacted with neat alcohol in presence of inorganic base, followed by isolating Desloratadine on addition of excess water in crystalline form.

L'invention concerne un procédé amélioré pour la production de desloratadine, comprenant les étapes suivantes : la loratadine est mise en réaction avec de l'alcool absolu en présence d'une base inorganique, puis la desloratadine est isolée par addition d'eau en excès sous forme cristalline.

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