A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5377 (2006.01) A61K 31/453 (2006.01) A61K 31/454 (2006.01) A61K 31/5365 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2660431
The invention is directed to a method for alleviating respiratory depression in a subject as a result of disease of pharmacological agents such as opiates, opioids or barbiturates. The invention also discloses pharmaceutical compositions for use with the method, the composition containing in combination, an analgesic, anaesthetic, or a sedative and a positive allosteric AMPA receptor modulator in an amount sufficient to reduce or inhibit respiratory depression caused by the analgesic, anaesthetic, or sedative.
L'invention concerne un procédé permettant d'atténuer la dépression respiratoire chez un sujet suite à une intoxication médicamenteuse due à des agents pharmacologiques, tels que des opiacés, des opioïdes ou des barbituriques. L'invention concerne également des compositions pharmaceutiques destinées à être utilisées dans ce procédé, ces compositions contenant, de façon combinée, un analgésique, un anesthésique, ou un sédatif et un modulateur allostérique positif des récepteurs AMPA en quantité suffisante pour atténuer ou inhiber la dépression respiratoire causée par l'analgésique, l'anesthésique ou le sédatif.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Governors Of The University Of Alberta
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