Nucleic acid constructs containing genes encoding transport...

Details Nucleic acid constructs containing genes encoding transport... Nucleic acid constructs containing genes encoding transport...

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A61K 48/00 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/67 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2204332

Nucleic acid constructs are disclosed which possess a nuclear retention signal which is linked, downstream in the reading direction, to a transgene. The nuclear retention signal can regulate the presence of the transcription product in the cell nucleus or else the intracellular transport of the transcription product.

ADN synthétique avec signal de rétention nucléaire, relié en aval dans la direction de lecture à un transgène. Le signal de rétention nucléaire peut réguler la présence du produit de transcription dans le noyau de la cellule ou bien le transport intracellulaire du produit de transcription.

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