Method for decreasing self-association of polypeptides

Details Method for decreasing self-association of polypeptides Method for decreasing self-association of polypeptides

A - Human Necessities

61

K

A61K 38/28 (2006.01) A61K 9/00 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2309955

Methods for decreasing the tendency for a polypeptide drug to self-associate are disclosed. The methods utilize histidine compounds and allow for more efficient delivery of polypeptide agents using transdermal delivery techniques.

L'invention concerne des procédés permettant de réduire la tendance à l'association spontanée d'un médicament constitué de polypeptides. Ces procédés, qui utilisent des composés d'histidine, permettent un apport plus efficace des agents polypeptidiques par des techniques d'administration percutanées.

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