Cell binding agent conjugates of analogues and derivatives...

Details Cell binding agent conjugates of analogues and derivatives... Cell binding agent conjugates of analogues and derivatives...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 47/48 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2076465

-63- Novel cytotoxic agents comprising a cell binding agent chemically linked to one or more analogue or derivative of CC-1065 are described. The therapeutic use of the cytotoxic agents is else described. These cytotoxic agents have therapeutic use because they deliver the cytotoxic drugs to a specific cell population in a targeted fashion.

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