Collagen-based delivery matrix

Details Collagen-based delivery matrix Collagen-based delivery matrix

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 38/18 (2006.01) A61L 27/00 (2006.01) C07K 14/78 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2223427

A collagen-based delivery matrix including collagen particles, wherein each of the particles has a diameter between 5 µm and 850 µm and, when suspended in an aqueous solution at a pH of about 7.0, has a net charge density between - 20 moles/mole collagen and -500 moles/mole collagen, or between +20 moles/mole collagen and +250 moles/mole collagen. Also disclosed are methods of preparing and using such a delivery matrix.

L'invention concerne une matrice d'administration à base de collagène comprenant des particules de collagène, où chacune des particules a un diamètre entre 5 µm et 850 µm et, lorsqu'elles sont en suspension dans une solution aqueuse ayant un pH d'environ 7,0, elles ont une densité nette de charge comprise entre -20 moles/mole de collagène et -500 moles/mole de collagène ou entre +20 moles/mole de collagène et +250 moles/mole de collagène. L'invention concerne également des procédés pour préparer et utiliser une telle matrice d'administration.

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