Process for producing levodione

Details Process for producing levodione Process for producing levodione

C - Chemistry, Metallurgy

12

P

C12P 7/26 (2006.01) C12N 9/02 (2006.01) C12N 15/53 (2006.01)

Patent

CA 2474802

An enone reductase characterized by a molecular mass of 61,300 .plusmn. 5,000 Da; NADPH and NADH as co-factor; a temperature optimum of 55-60~C at pH 7.4; a pH optimum of 4.5-8.5 and a substrate specificity on .alpha.,.beta.- unsaturated ketones, especially derived from a yeast and a process for the preparation of levodione from ketoisophorane.

Enone réductase caractérisée par une masse moléculaire de 61.300 .plusmn. 5.000 Da; NADPH et NADH en tant co-facteur ; température optimum de 55-60 ·C pour un pH de 7,4; pH optimum de 4,5-8,5 et substrat spécifique sur des cétones .alpha., .beta.-insaturées provenant d'une levure et procédé servant à préparer lévodione à partir de cétoisophorane.

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