Methods of using a somatostatin analogue

Details Methods of using a somatostatin analogue Methods of using a somatostatin analogue

A - Human Necessities

61

K

A61K 38/31 (2006.01) A61P 1/04 (2006.01) A61P 1/12 (2006.01) A61P 1/14 (2006.01) A61P 1/18 (2006.01) A61P 3/08 (2006.01) A61P 5/02 (2006.01) A61P 5/08 (2006.01) A61P 5/18 (2006.01) A61P 5/48 (2006.01) A61P 9/02 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 17/02 (2006.01) A61P 17/06 (2006.01)

Patent

CA 2335654

The present invention is directed to a method of treating one or more of the following disease and/or conditions, which comprises administering to a patient in need thereof the compound H-g(b)-D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys- Thr-NH2, where the Cysteines are bonded by a disulfide bond, or a pharmaceutically acceptable salt thereof, most preferably the acetate salt of the compound, in the treatment of certain diseases and/or conditions such as gastroenterological conditions and/or diseases, endocronological diseases and/or conditions, various types of cancers and conditions associated with cancer such as cancer cachexia and in the treatment of hypotension and panic attacks.

La présente invention concerne un procédé de traitement d'une ou plusieurs des maladies et/ou conditions suivantes. Ce procédé consiste à administrer à un patient le composé H-.beta.-D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH¿2?. Les cystéines sont liées par une liaison disulfure ou un sel pharmaceutiquement acceptable de ces dernières, de préférence, le sec acétate du composé, pour traiter certaines maladies et/ou états tels que des conditions et/ou maladies gastroentérologiques, des maladies et/ou des états endocrinologiques, divers types de cancers et états associés à un cancer tel qu'une cachexie de cancer et dans le traitement de l'hypotension et des crises de panique.

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