C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/26 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/55 (2006.01) C07K 16/24 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2337511
Compositions having IL-2-like activity and their use in the treatment or prevention of undesirable immune reactions such as graft rejection or autoimmune disorders, for example, rheumatoid arthritis. These compositions are defined as: a) peptides from N-terminus from IL-2 inhibiting or mimicking the binding of helix A of IL-2 to a subunit of an IL-2R, inducing phosphorylation of the submit of the IL-2R; or b) antibodies which recognize the peptide of the invention, and the therapeutic use of these antibodies.
L'invention concerne des compositions ayant une activité de type YL-2 et leur utilisation dans le traitement ou la prévention de réactions immunes indésirables telles que le rejet d'une greffe ou des troubles auto-immuns, par exemple, l'arthrite rhumatoïde. Ces compositions sont définies comme a) des peptides de N-terminaison de YL-2 inhibant ou imitant la phosphorylation de la sous-unité du YL-2; ou b) des anticorps reconnaissant le peptide faisant l'objet de cette invention et l'utilisation thérapeutique de ces anticorps.
Alzari Pedro
Eckenberg Ralph
Goldberg Michel
Mazie Jean-Claude
Moreau Jean-Louis
Institut Pasteur
Robic
LandOfFree
Peptides of il-2 and derivatives thereof and their use as... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptides of il-2 and derivatives thereof and their use as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides of il-2 and derivatives thereof and their use as... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1344260