Anticancer antibiotic mi43-37f11 substance, the production...

C - Chemistry – Metallurgy – 07 – D

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167/180, 195/87,

C07D 311/76 (2006.01) A61K 31/365 (2006.01) C12P 17/06 (2006.01)

Patent

CA 2017767

As a new antibiotic is provided a compound, now nominated as MI43-37F11 substance, which has formula Image This MI43-37F11 substance has an antitumor activity, an activity to enhance the production of interleukin-1 in vivo in a mammalian, and an activity to activate a macrophage in vivo in a mammalian. MI43-37F11 substance may be produced by cultivation of Streptoverticillium eurocidicum MI43-37F11 strain identified as FERM BP-2783.

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