Method and composition for treatment and/or prevention of...

A - Human Necessities – 61 – K

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Details

A61K 38/40 (2006.01) A01N 63/02 (2006.01) A61K 31/00 (2006.01) A61K 38/01 (2006.01) A61L 2/16 (2006.01)

Patent

CA 2394997

The present invention relates to a new composition, use and method to improve the cure of infections caused by antibiotic resistant microbial pathogens, in particular beta-lactam resistant microorganisms. Lactoferrin (LF) or Lactoferricin (LFC) can be administrated alone or in combination with antibiotic to affect growth, physiology and morphology of targeted microorganism. Lactoferrin increase susceptibility and can reverse resistance of microorganism to antibiotics.

L'invention concerne une composition, son utilisation et un procédé permettant d'améliorer le traitement d'infections dues à des pathogènes microbiens résistants aux antibiotiques, notamment des micro-organismes résistants aux bêta-lactamines. On peut administrer de la lactoferrine (LF) ou de la lactoferricine (LFC) seules ou en combinaison avec un antibiotique afin d'affecter la croissance, la physiologie et la morphologie du micro-organisme ciblé. La lactoferrine augmente la susceptibilité du micro-organisme aux antibiotiques et peut inverser sa résistance aux antibiotiques.

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