Multimers of receptor-binding ligands

Details Multimers of receptor-binding ligands Multimers of receptor-binding ligands

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 38/22 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C07K 14/575 (2006.01) C07K 14/61 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/16 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12N 15/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2510751

The invention relates to the provision of oligomeric polypeptides (dimers, trimers, etc) comprising the ligand binding domains of cytokines which are linked via flexible polypeptide linker molecules. The linker molecules optionally comprise protease sensitive sites to modulate the release of biologically active cytokines when administered to a human or animal subject.

L'invention a trait à des polypeptides oligomériques (dimères, trimères, etc.) comprenant des domaines de liaison aux ligands de cytokines, lesdits domaines étant liés par l'intermédiaire de molécules de liaison de polypeptide flexibles. Les molécules de liaison contiennent éventuellement des sites sensibles aux protéases, de façon à moduler la libération de cytokines biologiquement actives lorsqu'elles sont administrées à un sujet humain ou animal.

Affiliated with

Also associated with

Rating

Multimers of receptor-binding ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Multimers of receptor-binding ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multimers of receptor-binding ligands will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1345120