Thrombin inhibitor

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/81 (2006.01) A61K 38/57 (2006.01) A61K 49/00 (2006.01) A61P 7/02 (2006.01) C12N 9/74 (2006.01) C12N 15/12 (2006.01) C12Q 1/56 (2006.01)

Patent

CA 2691243

The invention relates to thrombin inhibitors derived from the salivary glands of haematophagous arthropods and in particular to bivalent and trivalent thrombin inhibitors that act by interacting with thrombin at two or three different sites.

La présente invention concerne des inhibiteurs de la thrombine dérivés des glandes salivaires d'arthropodes hématophages et en particulier des inhibiteurs bivalents et trivalents de la thrombine qui agissent au moyen d'une interaction avec la thrombine sur deux ou trois sites différents.

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