Methods and compositions relating to zpa polypeptides

C - Chemistry – Metallurgy – 07 – K

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C07K 14/46 (2006.01)

Patent

CA 2651199

The present invention provides ZPA polypeptides, antibodies, nucleic acid molecules, antagonists, agonists, potentiators and compositions relating to ZPA polypeptides, and methods of identifying, making and using the same, that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides model systems for the intrinsic apoptotic pathway.

La présente invention concerne des polypeptides ZPA et des anticorps, des molécules d'acide nucléique, des antagonistes, des agonistes, des potentialisateurs et des compositions se rapportant aux polypeptides ZPA, ainsi que des procédés d'identification, de fabrication et d'utilisation desdits polypeptides qui sont utiles pour le traitement et la prévention de maladies et pour le diagnostic médical et la recherche. La présente invention concerne également des systèmes modèles de la voie apoptotique intrinsèque.

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