Microimplants for ocular administration

A - Human Necessities – 61 – F

Patent

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A61F 9/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2598512

Implants and microimplants are provided comprising homogeneous mixtures of active ingredient and bioerodible polymer, including microimplant having diameters of (0.019) inches or less and which can be delivered to the eye using self-sealing methods. Methods of manufacturing the implants and microimplants are provided that yield batches of highly uniform implants and microimplants within vary narrow tolerance ranges.

La présente invention concerne des implants et des micro-implants qui comprennent des mélanges homogènes d'un ingrédient actif et d'un polymère bioérodable, y compris des micro-implants ayant des diamètres de 0,019 pouces ou moins et qui peuvent être administrés dans l~AEil en utilisant des procédés autoscellants. L~invention concerne également des procédés de fabrication des implants et des micro-implants qui produisent des lots d~implants et de micro-implants très uniformes dans des plages de tolérances très étroites.

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