A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 31/517 (2006.01)
Patent
CA 2476621
The invention relates to powder inhalation for the treatment of migraines, comprising the CGRP-antagonists 1-[N2~-[3,5-dibrom-N-[[4-(3,4-dihydro-2(1H)- oxochinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4- pyridinyl)-piperazin [BIBN4096] of formula I as an active substance base in the form of spherical nanostructured particles and a method for the production thereof.
L'invention concerne une poudre d'inhalation destin~e au traitement des migraines, contenant, en tant que base d'agent actif, l'antagoniste de CGRP repr~sent~ par la formule (I) 1-[N?2´-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxochinazoline-3-yl)-1-pip~ridinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-pip~razine [BIBN4096] sous forme de particules sph~riques nanostructur~es, ainsi qu'un proc~d~ de fabrication de ladite poudre.
Trunk Michael
Weiler Claudius
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Fetherstonhaugh & Co.
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