A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/00 (2006.01) A61K 31/138 (2006.01) A61K 31/19 (2006.01) A61P 25/00 (2006.01) A61P 25/08 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61K 49/00 (2006.01)
Patent
CA 2629463
This invention provides a method for treating a mammalian subject afflicted with a disorder associated with reduced neurogenesis in the subject's hippocampal dentate gyrus which comprises administering to the subject a therapeutically effective amount of a compound which increases cerebral blood volume in the subject's hippocampal dentate gyrus by a percentage greater than that by which it increases the cerebral blood volume in the subject's hippocampal CAl region, thereby treating the subject.
Cette invention concerne un procédé pour traiter un sujet mammifère atteint d'un trouble associé à une neurogenèse réduite dans le gyrus denté hippocampique du sujet, ledit procédé comprenant l'administration au sujet d'une quantité efficace d'un point de vue thérapeutique d'un composé qui augmente le volume sanguin cérébral dans le gyrus denté hippocampique du sujet à un pourcentage supérieur à celui par lequel il augmente le volume sanguin cérébral dans la région CA1 hippocampique du sujet, permettant ainsi de traiter le sujet.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Trustees Of Columbia University In The City Of New York
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