C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/02 (2006.01) C12N 5/0775 (2010.01)
Patent
CA 2563872
This invention relates to methods of producing a substantially homogenous population of mesenchymal stem cells derived from embryonic stem cells. Also, disclosed is a homogenous population of mesenchymal stem cells capable of further differentiating into a variety of specific cell types, characterized by various morphological factors and cell-specific markers. The compositions and methods described in this disclosure are useful for a variety of commercially important diagnostic, drug screening, and therapeutic applications.
L'invention concerne des procédés de production d'une population sensiblement homogène de cellules souches mésenchymateuses dérivées de cellules souches embryonnaires. L'invention concerne également une population homogène de cellules souches mésenchymateuses capables d'une différentiation plus poussée en une variété de types de cellules spécifiques, caractérisée par différents facteurs morphologiques et marqueurs à spécificité cellulaire. Les compositions et procédés selon l'invention sont utiles à une variété de diagnostics, d'un dépistage systématique des drogues et d'applications thérapeutiques d'importance commerciale.
Pike J. Wesley
Shevde Nirupama K.
Gowling Lafleur Henderson Llp
Wisconsin Alumni Research Foundation
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