Oxadiazole-2-oxides as antischistosomal agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 271/08 (2006.01) A61K 31/4245 (2006.01) A61P 33/12 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2733190

The invention provides 1,2,5-oxadiazole-containing compounds of Formula (I), wherein R1, A, and R2 are as defined herein, that are useful in treating schistosomiasis. The invention also provides a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, and a method of of treating schistosomiasis in a mammal.

L'invention concerne des composés contenant du 1,2,5-oxadiazole de la formule (I), R1, A et R2 étant tels que définis ici, qui sont utiles pour traiter une schistosomiase. L'invention concerne également une composition comprenant un support pharmaceutiquement acceptable et au moins un composé de l'invention, et un procédé de traitement de la schistosomiase chez un mammifère.

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